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Trimethoprim

Trimethoprim

Region: Hunan
Minimum Order Quantity:
Monthly Production Capacity:
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Detailed Description
  • Packaging Information: 25KG/DRUM
  • Payment Terms: T/T,L/C,DP,BANK CONTRACT
  • Main Sales Markets: North America, Central/South America, Western Europe, Eastern Europe, Australasia, Asia, Middle East, Africa
  • Sample Provided: no

 

Hot sell Trimethoprim/TMP/38-70-5
1.Cas No.:38-70-5
2.Color:white
3.Standard:CP/USP
4.Packing:25kg/drum

 

Hot sell Trimethoprim/TMP/38-70-5
1.Cas No.:38-70-5
2.Color:white
3.Standard:CP/USP
4.Packing:25kg/drum

Trimethoprim/TMP/CAS NO.:38-70-5

1.CAS NO.:38-70-5

2.Color:White powder

3.Standard:CP/USP

4.Packing:25kg/drum

 

Trimethoprim (INN) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections. It belongs to the class of chemotherapeutic agents known as dihydrofolate reductase inhibitors. Trimethoprim was formerly marketed by GlaxoSmithKline under trade names including Proloprim, Monotrim and Triprim; but these trade names have been licensed to various generic pharmaceutical manufacturers. In clinical use it is often abbreviated TRI or TMP; its common laboratory abbreviation is W.

Items

Standard

Results

Appearance

White or yellowish-white powder

White powder

Solubility

Very slightly soluble in water, 

slightly soluble in alcohol.

Very slightly soluble in water, 

slightly soluble in alcohol.

•Identification

A: Melting point

199-203

201.0-201.4

B: Specific absorbance

Max.287nm: 240-250

243

C: IR-spectrum

Complies with reference spectrum

Complies with reference spectrum

D: Chemical reaction

Green fluorescence at 365nm

Green fluorescence at 365nm

Appearance of solution

Not more intensely colored than 

Reference Solution BY7

Less intensely colored than reference solution BY7

Related substances

Method A by HPLC:

 

 

Impurity F

≤0.1%

0.05%

Any single impurity

≤0.1%

<0.1%

Total impurities

≤0.2%

<0.2%

Method B by HPLC:

 

 

Any single impurity

≤0.1%

<0.1%

Total impurities

≤0.2%

<0.2%

Heavy metals

≤20ppm

<

20ppm

Residual methanol

≤3000ppm

Not detected

Residual DMSO

≤5000ppm

Not detected

Residual acetic acid

≤5000ppm

Not detected

Impurity K(aniline) by GC

≤5ppm

Not detected

Loss on drying

≤0.5%

0.3%

Sulphated ash

≤0.1%

0.02%

Assay 

98.5-101.0%

99.71%

Particle size

100% pass 300 mesh

100% pass 300 mesh

 

 

 

 

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Address: Changsha Hunan China

City: Changsha

Contact: Edon

TEL: -731-88960813

Fax: -731-88960820

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