弹框
Join Free For Buyer|Sign In

Professional Online Trade Platform for API, Preparation and Pharmaceutical Machinery and Equipment_EN-CPhI.cn

You are here:  Home >>  News >>  Research & Development >>  BMJ journal deems opioid dependency implant more favourable than tablets

BMJ journal deems opioid dependency implant more favourable than tablets

march 30, 2020 By pharmatimes
Tag: opioid , tablets , BMJ

A new benefit-risk study published in the BMJ Evidence Based Medicine has deemed a new implant preventing withdrawal symptoms for patients with opioid dependency more favourable than sublingual tablets.

Undertaken by the Drug Safety Research Unit (DSRU) in Southampton, the research demonstrated that delivering buprenorphine by subcutaneous implant, rather than in tablet/film-form under the tongue, was favourable in terms of compliance and convenience, quality of life measures and reduced illicit opioid-use.

In the study, the benefits outweighed the risks of having the implant including infection at the insertion site, migrated or missing implants, allergic reactions and clinically significant implant breakages.

The researchers noted that this was when looking specifically at benefits and risks of the mode of delivering the drug buprenorphine, not the general risks and benefits of the drug itself.

While the opioid epidemic in the USA is well documented, Europe also has an estimated 1.3 million high-risk opioid users, in which buprenorphine can be used as a substitution drug for opioid dependency.

Professor Saad Shakir, director of the DSRU, said: “This publication explains how a semi-quantitative benefit-risk tool is used to support risk management and provides more robust evidence than the conventional method.”

The European Medicines Agency (EMA) requested a systematic benefit-risk assessment to compare buprenorphine implant to sublingual buprenorphine as part of the EU license application.

 

Register as Visitor to CPhI China 2020!

Register as Visitor to CPhI China 2020!

-----------------------------------------------------------------------
Editor's Note:

En-CPhI.CN is a vertical B2B online trade platform serving the pharmaceutical industry,

for any copyright disputes involved in the articles,

please email: Julia.Zhang@imsinoexpo.com to motify or remove the content.

Readers'Comments
Add a comment
Click here to Login or to Register for free. You will be taken back to your selected item after Login/Registration.
More>> MarketNews
More>> Editors’Picks
More>> TopStories
More>> HotTags
Follow Us
CPhI Online Trade Platform: Worldwide|English|中国站
Customer Service:  86-400 610 1188 (9: 00-18: 00, Mon-Fri)
About Us| Contact Us| Terms of Services| Privacy Policy| Intellectual Property Statement| Links | Site Map
Copyright 2006-20 Shanghai Sinoexpo Informa Markets International Exhibition Co. Ltd (All Rights Reserved). ICP 05034851-53